Gene Expression Mapping of Histone Deacetylases and Co-factors, and Correlation with Survival Time and H-HRMAS Metabolomic Profile in Human Gliomas
نویسندگان
چکیده
Laboratoire de Biochimie et Biologie Moléculaire, Hôpitaux Universitaires de Strasbourg, Nouvel Hôpital Civil, 1 place de l’hôpital, 67091 Strasbourg Cedex, France, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC)/CNRS UMR 7104/ INSERM U 964/Université de Strasbourg, 1 rue Laurent Fries, 67404 Illkirch, France, Institut Clinique de la Souris, 1 rue Laurent Fries, 67404 Illkirch, France, Department of Neurosurgery, Hôpitaux Universitaires de Strasbourg, avenue Molière, 67085 Strasbourg Cedex, France, Centre Paul Strauss, 3 rue de la porte de l’Hôpital 67065 Strasbourg, Cedex, France, Department of Biophysics and Nuclear Medicine, Hôpitaux Universitaires de Strasbourg, CHU de Hautepierre, avenue Molière, 67200 Strasbourg Cedex, France.
منابع مشابه
Gene Expression Mapping of Histone Deacetylases and Co-factors, and Correlation with Survival Time and 1H-HRMAS Metabolomic Profile in Human Gliomas
Primary brain tumors are presently classified based on imaging and histopathological techniques, which remains unsatisfaying. We profiled here by quantitative real time PCR (qRT-PCR) the transcripts of eighteen histone deacetylases (HDACs) and a subset of transcriptional co-factors in non-tumoral brain samples from 15 patients operated for epilepsia and in brain tumor samples from 50 patients d...
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